Sanofi and Sobi Present P-III Study (XTEND-Kids) Results of Altuviiio for Severe Hemophilia A at ISTH 2023
Shots:
- The P-III study evaluating Altuviiio (50IU/kg, qw for 52wks.) in 75 patients aged ≤12yrs. The trial met 1EPs with no inhibitor development to factor VIII detected, median & mean ABRs were 0.00 & 0.89
- 64% had zero bleeding episodes, 82% & 88% had zero joint bleeds & spontaneous bleeds, was well-tolerated with a similar safety profile to (XTEND-1) trial confirming safety and efficacy in adults & children with highly effective bleed protection. The 2EPs incl. ABR & maintenance of factor VIII activity above pre-specified levels
- No serious allergic reactions, anaphylaxis, or embolic or thrombotic events were seen. Altuviiio was approved in the US for routine prophylaxis, on-demand treatment to control bleeding episodes & perioperative management in adults & children with hemophilia A
Ref: Sanofi | Image: Sanofi
Related News:- Sanofi and Sobi Report P-III Study (XTEND-Kids) Results of Altuviiio for the Treatment of Hemophilia A in Children Aged <12 Years
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Neha is a Senior Editor at PharmaShots. She is passionate and very enthusiastic about recent updates and developments in the life sciences and pharma industry. She covers Biopharma, MedTech, and Digital health segments along with different reports at PharmaShots. She can be contacted at connect@pharmashots.com.
